@mfied makes an interesting case for utilizing Sproutcore for web app development.
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Via Building interactive web apps with SproutCore | Minified:
Currently, Backbone gets a lot of the attention, and rightly so, it’s a great framework. In this post though, I want to demonstrate a use case where I believe SproutCore 2 excels — building interactive web apps.
Developing in SproutCore takes away the need to update and re-render views, and the focus shifts entirely to managing and updating the client side data model.